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August 22, 2020

FEATURED ARTICLE

Impact of Famotidine Use on Clinical Outcomes of Hospitalized COVID-19 Patients

Jeffrey F. Mather, MS, and colleagues share new findings: Famotidine use in hospitalized COVID-19 patients was significantly associated with reduction in death, lower risk of combined outcome of mortality and intubation, and demonstrated lower levels of serum markers for severe disease.

COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions

COVID-19 has transformed many aspects of medical practice, including the field of transplantation. Here, the authors describe a single-center approach to creating a generalizable, comprehensive, and graduated set of recommendations to respond to the challenges posed by these conditions, and the underlying principles guiding such decisions.

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Age-Dependent Sensory Impairment in COVID-19 Infection and its Correlation with ACE2 Expression

Among individuals who tested positive for COVID-19, smell and taste sensations were significantly less impaired among children than among adults. Sensory impairment was correlated with recent data of angiotensin-converting enzyme 2 expression in the corresponding age groups. This is the first report to compare sensory impairment in children and adults testing positive for COVID-19.

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Corticosteroids in the Management of Pregnant Patients With COVID-19

Recent evidence supports the use of an early, short course of glucocorticoids in patients with COVID-19 who require mechanical ventilation or oxygen support. Here, the authors summarize the evidence supporting steroid therapy in the management of patients with acute respiratory distress syndrome and COVID-19 and to elaborate on key modifications for the pregnant patient.

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The Adverse Skin Reactions of Health Care Workers Using PPE for COVID-19

This study collected the results of a survey of adverse skin reactions caused by the use of PPE by healthcare workers in Hubei Province during the COVID-19 outbreak.

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PODCASTS

How Sports Medicine Physicians in the Military are Addressing the SARS-CoV-2 Virus [46:16]

Navigating the COVID-19 Information Overload [25:18]

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WEEKLY BRIEFINGS

Below are our additional COVID-19 resources to keep you informed.

COVID-19 Briefing Archive

COVID-19 Resources on Ovid®

Wolters Kluwer Health Clarity Hub

COVID-19 Resources for Nurses

Core Outcomes Set for Trials in People With COVID-19

The outcomes reported in trials in COVID-19 are extremely heterogeneous and of uncertain patient relevance, limiting their applicability for clinical decision-making. The aim of this workshop was to establish a core outcomes set for trials in people with suspected or confirmed COVID-19.

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Open Tracheostomy for COVID-19–Positive Patients

A case series describes a method of performing open tracheostomy for COVID-19 patients while minimizing potential aerosolization of the virus using typically available equipment and supplies.

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The Novel COVID-19 and Its Impact on Cardiovascular Disease

A summary of the cardiovascular impact of COVID-19 and some of the challenges that patients and the healthcare system will face during this pandemic

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Black Patients Are Less Likely to Present With Strokes During the COVID-19 Pandemic

The COVID-19 pandemic has led to a significant drop in telestroke volume. The impact seems to disproportionately affect Black patients.

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COVID-19–Associated Coagulopathy

COVID-19 is associated with a systemic coagulopathy  favoring thromboembolic complications, which occur in 15% to 30% of critically ill patients with COVID-19. The findings of this new study suggest that the systemic inflammatory response is a major contributor to COVID-19–associated coagulopathy, supporting the concept of thromboinflammation

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