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September 12, 2020

FEATURED ARTICLE

Can Urine Biomarkers Predict the Clinical Severity of COVID-19?

"To the best of our knowledge, there have been no reports of urinary biomarkers being used to evaluate COVID-19 disease activity, rather than evaluating the renal function of COVID-19 patients," says Katagiri, Daisuke MD, PhD and colleagues. "Our findings suggest that urinary biomarkers, especially β2MG and L-FABP, may assist with predicting severity at an early stage."

Early detection of COVID-19 in patients likely to develop severe manifestations enables appropriate interventions, including rapid ICU admission. 

Severe COVID-19 is a Microvascular Disease

Researchers propose that the COVID-19 triggers a unique endothelial response, endothelial exocytosis, which simultaneously activates two parallel pathways, microvascular inflammation and microvascular thrombosis, ultimately leading to hyperinflammation and diffuse thrombosis characteristic of severe COVID-19. 

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Outcomes After Tracheostomy in COVID-19 Patients

See how alterations to tracheostomy practices and processes may improve safety for both patients and healthcare workers performing the procedure in COVID-19 intubated patients.

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Determining Nursing Education Needs During a Rapidly Changing COVID-19 Environment

COVID-19 created an environment that required rapid implementation of procedures and processes to minimize transmission. This article describes strategies and methods employed to meet the training demands at a time when resources and supplies were limited. 

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Are Hospitals Safe? A Prospective Study on SARS-CoV-2 Prevalence and Outcome on Surgical Fracture Patients

Study describes clinical characteristics of fracture patients, including a closer look to hip fracture patients, and determine how epidemiological variables may have influenced on a higher vulnerability to SARS-CoV-2 infection, as the basis for the considerations needed to reintroduce elective surgery during the pandemic.

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STAY UPDATED BETWEEN WEEKLY BRIEFINGS

Below are our additional COVID-19 resources to keep you informed.

COVID-19 Briefing Archive

COVID-19 Resources on Ovid®

Wolters Kluwer COVID-19 Health Resources

COVID-19 Resources for Nurses

COVID-19: Implications for Supply Chain Management

While efforts to effectively treat and eradicate the coronavirus continue, so do the efforts of supply chains to support the provision of patient care in the event of a resurgence or future pandemic.

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Sports Ultrasound Training During a Pandemic: Developing a “Hands-on” Skill Through Distance Learning

For “hands-on” sports ultrasound teaching to continue during these uncertain times, the educational model must be adapted.

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Systemic Complications of COVID-19

The immune response to COVID-19 includes a cytokine storm that creates many life-threatening problems including coagulopathies, arrhythmias, and secondary infections. Here you'll learn more about the multisystem responses to the physical insults created by this corona virus.

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Decreased Mortality of COVID-19 With Renin-Angiotensin-Aldosterone System Inhibitors Therapy in Patients With Hypertension

A meta-analysis of the current studies to explore whether the use of ACE inhibitor/ARB was associated with disease severity and mortality in COVID-19 patients with hypertension.

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Role for Antimalarials in the Management of COVID-19

Insights into direct antiviral effects by antimalarials against severe COVID-19 and other viruses and their potential indirect effects on the host by avoiding exaggerated immune responses (reduced cytokine release, Toll-like receptor response, antigen presentation related to lysosomal processing).

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