November 28, 2020

FEATURED ARTICLE

Hydroxychloroquine and COVID-19: Lack of Efficacy and the Social Construction

of Plausibility

Although any hope of a positive effect was brought exclusively by some and not all of the observational studies, none of the 7 RCT published until now have found any benefit. From a sociological perspective, the HCQ controversy is a useful case study for understanding the construction of plausibility in a cultural context polarized into competing versions of reality, with different epistemologies and ideologies.

Use of Nonsteroidal Anti-inflammatory Drugs for COVID-19 Infection: Adjunct Therapy?

A thorough PubMed® literature review on the therapeutic use of NSAID provides a comprehensive perspective of the role of NSAIDs in treating COVID-19

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Grim News About Opioid Overdose Deaths During the COVID-19 Pandemic

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Varying Presentations of COVID-19 Across Different Age Groups

To better understand the varying presentations of COVID-19, authors review several case studies from the New England Journal of Medicine.

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Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in COVID-19

Aim of this study was to test whether a previously defined bacterial sepsis endotypes classifier recapitulates the same clinical and immunological endotypes in coronavirus disease 2019.

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COVID-19 Cardiovascular Registry Opens to Broader Research Community

All scientific researchers from across the U.S. are now able to submit research proposals to the American Heart Association’s Quality Research program to use its nationwide dataset from the COVID-19 CVD Registry Powered by Get With The Guidelines®. 

STAY UPDATED BETWEEN WEEKLY BRIEFINGS

Below are our additional COVID-19 resources to keep you informed.

COVID-19 Briefing Archive

COVID-19 Resources on Ovid®

Wolters Kluwer COVID-19 Health Resources

COVID-19 Resources for Nurses

Universal Screening for COVID-19 in Children Undergoing Orthopaedic Surgery

The COVID-19 pandemic has substantially altered the typical process around performing surgery to ensure protection of healthcare workers, patients, and their families. One safety precaution has been the implementation of universal preoperative screening for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This study examines the results of universal screening on children undergoing orthopaedic surgery.

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COVID-19 Quarantine Is More Detrimental Than Traditional Off-Season on Physical Conditioning of Professional Soccer Players

In soccer, practitioners are concerned about the effects of long-term detraining on players' conditioning, and caution is required when activities return.

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Lung Scans for Stroke Patients Could Provide Earlier COVID-19 Detection

Examination of the lungs via CTA scans helped researchers screen for and detect COVID-19 earlier than traditional nasal swab tests in acute stroke patients.

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COVID-19 Presenting as Fulminant Hepatic Failure: A Case Report

In this paper, the authors present a case of a young woman with SLE who developed severe abdominal pain, nausea and vomiting, rapidly progressing to acute hepatic failure and tested positive for SARS-CoV-2 infection. She had no respiratory symptoms.

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High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe COVID-19

This paper reports the treatment of pregnant patients with severe or critical coronavirus disease 2019 (COVID-19) with nitric oxide gas.

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